{"id":114,"date":"2021-06-29T08:24:52","date_gmt":"2021-06-29T08:24:52","guid":{"rendered":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/?p=114"},"modified":"2024-03-24T15:51:07","modified_gmt":"2024-03-24T14:51:07","slug":"la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve","status":"publish","type":"post","link":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/2021\/06\/29\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\/","title":{"rendered":"La troballa d’una prote\u00efna implicada en el principal c\u00e0ncer de fetge, Premi de Recerca Fundaci\u00f3 Dr. Antoni Esteve"},"content":{"rendered":"

El 2019, un grup del Centro Nacional de Investigaciones Cardiovasculares publicava a la revista Nature<\/em><\/a> dades rellevants al voltant de la implicaci\u00f3 de la prote\u00efna p38gamma en el desenvolupament del principal tipus de c\u00e0ncer primari de fetge<\/strong>. Es tracta del carcinoma hepatocel\u00b7lular, que afecta m\u00e9s d’un mili\u00f3 de persones a l’any a tot el m\u00f3n i pel qual actualment es disposa de poques opcions farmacol\u00f2giques. Ara, el tribunal internacional que cada dos anys concedeix el Premi de Recerca Fundaci\u00f3 Dr. Antoni Esteve ha considerat aquest article cient\u00edfic com la publicaci\u00f3 farmacol\u00f2gica m\u00e9s important publicada per un autor espanyol entre 2019 i 2020<\/strong>. Antonia Tom\u00e1s Loba, en nom de l’equip que dirigeix Guadalupe Sabio, rebr\u00e0 com a primera autora de l’article aquest guard\u00f3, dotat de 18.000 euros, en un acte de lliurament que, per motius sanitaris, se celebrar\u00e0 a la tardor en les instal\u00b7lacions del CNIC.<\/p>\n

L’article p38\u03b3 is essential for cell cycle progression and liver tumorigenesis<\/em><\/a> no nom\u00e9s descobreix com la prote\u00efna p38gamma est\u00e0 relacionada amb la divisi\u00f3 cel\u00b7lular en el fetge sin\u00f3 que tamb\u00e9 ha estudiat en ratolins qu\u00e8 passava quan se’ls indu\u00efa qu\u00edmicament el c\u00e0ncer de fetge amb o sense aquesta prote\u00efna. \u00abTant si faltava aquesta prote\u00efna com si es bloquejava la seva activitat amb un f\u00e0rmac, vam aconseguir retardar el desenvolupament del tumor\u00bb, assenyala Tom\u00e1s Loba. \u00abAquests resultats es podrien extrapolar a les persones, ja que hem vist que la p38gamma est\u00e0 augmentada en mostres humanes de pacients amb c\u00e0ncer hep\u00e0tic\u00bb, explica Guadalupe Sabio, directora d’aquest grup de recerca del CNIC.<\/strong><\/p>\n

\u00abAquest descobriment \u00e9s d’una gran import\u00e0ncia m\u00e8dica perqu\u00e8 identifica a p38gamma com un objectiu prometedor per al tractament del c\u00e0ncer de fetge. Els resultats es van obtenir utilitzant una excel\u00b7lent combinaci\u00f3 d’enfocaments farmacol\u00f2gics i gen\u00e8tics per estudiar el paper de p38gamma. L’an\u00e0lisi es va realitzar utilitzant tecnologies d’avantguarda en biologia cel\u00b7lular i molecular, imatges i biologia computacional\u00bb, explica Sabine Werner, de l’Escola Polit\u00e8cnica Federal de Zurich i membre del jurat del Premi de Recerca Fundaci\u00f3 Dr. Antoni Esteve juntament amb Xavier Guitart, del National Institute of Drug Abuse a Estats Units, i F\u00e8lix Bosch, director de la Fundaci\u00f3 Dr. Antoni Esteve.<\/strong><\/p>\n

\u00abL’estudi, per tant, ofereix una contribuci\u00f3 fonamental a la nostra comprensi\u00f3 de la progressi\u00f3 del cicle cel\u00b7lular en el fetge malalt i en regeneraci\u00f3 i obre noves vies per al tractament del c\u00e0ncer de fetge\u00bb, conclou Sabine Werner.<\/p>\n

L’equip del CNIC fa diversos anys que estudia una fam\u00edlia de prote\u00efnes, les p38 kinases, que s’activen quan les c\u00e8l\u00b7lules pateixen qualsevol mena d’estr\u00e8s. \u00abEstudiant amb detall l’estructura tridimensional de les prote\u00efnes vam observar que una d’elles, la p38gamma, era molt similar a la d’un altre grup de prote\u00efnes conegudes com a CDKs. Aquestes \u00faltimes \u2013apunta Sabio- es coneixen des de fa temps per estar relacionades amb el desenvolupament del c\u00e0ncer\u00bb.<\/p>\n

En estudis en el laboratori en col\u00b7laboraci\u00f3 amb cient\u00edfics del Centro Nacional de Investigaciones Oncol\u00f3gicas (CNIO) i Silvia Osuna, investigadora de la Universitat de Girona, van aprofundir en aquestes similituds amb les CDKs. Aix\u00ed, van veure que un inhibidor conegut de la CDK2, la perfenidona, tamb\u00e9 disminueix l’activitat de la p38gamma. D’aquesta manera, fent servir l’inhibidor es bloquejava la seva activitat i s’exercia una acci\u00f3 supressora de tumors.<\/p>\n

En col\u00b7laboraci\u00f3 amb l’Hospital Universitari de Salamanca, aquest grup del CNIC tamb\u00e9 ha comprovat que la quantitat d’aquesta prote\u00efna en fetge augmenta amb la fibrosi hep\u00e0tica. Una condici\u00f3 que precedeix el c\u00e0ncer i \u00e9s molt major en els pacients amb c\u00e0ncer de fetge. \u00abEn el futur es podria tractar aquest tipus de c\u00e0ncer amb algun medicament que inhib\u00eds espec\u00edficament a la p38gamma\u00bb<\/strong>, suggereixen els investigadors. \u00abL’avantatge enfront altres vies \u00e9s que els nostres resultats apunten que la inhibici\u00f3 de la p38gamma no afectaria altres teixits que estan en contant proliferaci\u00f3 com l’intest\u00ed o el p\u00e8l\u00bb, afegeixen.<\/p>\n

Els membres del jurat internacional del Premi de Recerca Fundaci\u00f3 Dr. Antoni Esteve tamb\u00e9 han volgut recon\u00e8ixer amb una menci\u00f3 honor\u00edfica l’article publicat el 2019 a la revista Nature Metabolism<\/em><\/a> pel grup del Instituto de Investigaci\u00f3n Sanitaria de Santiago i la Universitat de Santiago de Compostela, que coordinen Rub\u00e9n Nogueiras i Luisa Seoane, en qu\u00e8 descobreixen el mecanisme mitjan\u00e7ant el qual alguns f\u00e0rmacs que s’utilitzen per al tractament d’altres malalties disminueixen tamb\u00e9 el pes corporal<\/strong>. Aquesta menci\u00f3 honor\u00edfica se suma al Premi de Recerca Fundaci\u00f3 Dr. Antoni Esteve que ja va rebre l’equip de Nogueiras el 2017 per demostrar l’efic\u00e0cia d’un f\u00e0rmac per a la diabetis en la reducci\u00f3 de pes.<\/p>\n

Aquest \u00e9s el disset\u00e8 lliurament del Premi de Recerca Fundaci\u00f3 Dr. Antoni Esteve<\/strong>, que es concedeix al millor treball de farmacologia publicat per un autor espanyol en els \u00faltims dos anys en qualsevol dels seus aspectes (disseny, s\u00edntesi, desenvolupament gal\u00e8nic, avaluaci\u00f3 cl\u00ednica o de laboratori, \u00fas, etc\u00e8tera).<\/p>\n","protected":false},"excerpt":{"rendered":"

El 2019, un grup del Centro Nacional de Investigaciones Cardiovasculares publicava a la revista Nature dades rellevants al voltant de la implicaci\u00f3 de la prote\u00efna p38gamma en el desenvolupament del principal tipus de c\u00e0ncer primari de fetge. Es tracta del carcinoma hepatocel\u00b7lular, que afecta m\u00e9s d’un mili\u00f3 de persones a l’any a tot el m\u00f3n<\/p>\n","protected":false},"author":356,"featured_media":116,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2],"tags":[10],"tipo":[20],"class_list":["post-114","post","type-post","status-publish","format-standard","has-post-thumbnail","category-uncategorized","tag-cancer-de-fetge","tipo-actualitat"],"acf":[],"yoast_head":"\nLa troballa d'una prote\u00efna implicada en el principal c\u00e0ncer de fetge, Premi de Recerca Fundaci\u00f3 Dr. Antoni Esteve - Fundaci\u00f3 Dr. Antoni Esteve<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/2021\/06\/29\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"La troballa d'una prote\u00efna implicada en el principal c\u00e0ncer de fetge, Premi de Recerca Fundaci\u00f3 Dr. Antoni Esteve - Fundaci\u00f3 Dr. Antoni Esteve\" \/>\n<meta property=\"og:description\" content=\"El 2019, un grup del Centro Nacional de Investigaciones Cardiovasculares publicava a la revista Nature dades rellevants al voltant de la implicaci\u00f3 de la prote\u00efna p38gamma en el desenvolupament del principal tipus de c\u00e0ncer primari de fetge. Es tracta del carcinoma hepatocel\u00b7lular, que afecta m\u00e9s d’un mili\u00f3 de persones a l’any a tot el m\u00f3n\" \/>\n<meta property=\"og:url\" content=\"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/2021\/06\/29\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\/\" \/>\n<meta property=\"og:site_name\" content=\"Fundaci\u00f3 Dr. Antoni Esteve\" \/>\n<meta property=\"article:published_time\" content=\"2021-06-29T08:24:52+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-03-24T14:51:07+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/wp-content\/uploads\/sites\/3\/2021\/06\/iStock-1212392754.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1365\" \/>\n\t<meta property=\"og:image:height\" content=\"768\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Pol Morales\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrit per\" \/>\n\t<meta name=\"twitter:data1\" content=\"Pol Morales\" \/>\n\t<meta name=\"twitter:label2\" content=\"Temps estimat de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minuts\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/2021\\\/06\\\/29\\\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/2021\\\/06\\\/29\\\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\\\/\"},\"author\":{\"name\":\"Pol Morales\",\"@id\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/#\\\/schema\\\/person\\\/a1687300e23b0ac2ab84495a03182823\"},\"headline\":\"La troballa d’una prote\u00efna implicada en el principal c\u00e0ncer de fetge, Premi de Recerca Fundaci\u00f3 Dr. Antoni Esteve\",\"datePublished\":\"2021-06-29T08:24:52+00:00\",\"dateModified\":\"2024-03-24T14:51:07+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/2021\\\/06\\\/29\\\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\\\/\"},\"wordCount\":911,\"commentCount\":0,\"image\":{\"@id\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/2021\\\/06\\\/29\\\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/wp-content\\\/uploads\\\/sites\\\/3\\\/2021\\\/06\\\/iStock-1212392754.jpg\",\"keywords\":[\"c\u00e0ncer de fetge\"],\"articleSection\":[\"Uncategorized\"],\"inLanguage\":\"ca\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/2021\\\/06\\\/29\\\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/2021\\\/06\\\/29\\\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\\\/\",\"url\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/2021\\\/06\\\/29\\\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\\\/\",\"name\":\"La troballa d'una prote\u00efna implicada en el principal c\u00e0ncer de fetge, Premi de Recerca Fundaci\u00f3 Dr. Antoni Esteve - Fundaci\u00f3 Dr. Antoni Esteve\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/2021\\\/06\\\/29\\\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/2021\\\/06\\\/29\\\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/wp-content\\\/uploads\\\/sites\\\/3\\\/2021\\\/06\\\/iStock-1212392754.jpg\",\"datePublished\":\"2021-06-29T08:24:52+00:00\",\"dateModified\":\"2024-03-24T14:51:07+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/#\\\/schema\\\/person\\\/a1687300e23b0ac2ab84495a03182823\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/2021\\\/06\\\/29\\\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\\\/#breadcrumb\"},\"inLanguage\":\"ca\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/2021\\\/06\\\/29\\\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"ca\",\"@id\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/2021\\\/06\\\/29\\\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\\\/#primaryimage\",\"url\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/wp-content\\\/uploads\\\/sites\\\/3\\\/2021\\\/06\\\/iStock-1212392754.jpg\",\"contentUrl\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/wp-content\\\/uploads\\\/sites\\\/3\\\/2021\\\/06\\\/iStock-1212392754.jpg\",\"width\":1365,\"height\":768,\"caption\":\"\\\/iStock\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/2021\\\/06\\\/29\\\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Portada\",\"item\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"La troballa d’una prote\u00efna implicada en el principal c\u00e0ncer de fetge, Premi de Recerca Fundaci\u00f3 Dr. Antoni Esteve\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/#website\",\"url\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/\",\"name\":\"Fundaci\u00f3 Dr. Antoni Esteve\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"ca\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/#\\\/schema\\\/person\\\/a1687300e23b0ac2ab84495a03182823\",\"name\":\"Pol Morales\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"ca\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/6c5799ee792676e22d7558d1f109ddf8098905c75b14bcf15d23ecb7f422b189?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/6c5799ee792676e22d7558d1f109ddf8098905c75b14bcf15d23ecb7f422b189?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/6c5799ee792676e22d7558d1f109ddf8098905c75b14bcf15d23ecb7f422b189?s=96&d=mm&r=g\",\"caption\":\"Pol Morales\"},\"url\":\"https:\\\/\\\/diarisanitat.cat\\\/fundacio-dr-antoni-esteve\\\/author\\\/pmorales\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"La troballa d'una prote\u00efna implicada en el principal c\u00e0ncer de fetge, Premi de Recerca Fundaci\u00f3 Dr. Antoni Esteve - Fundaci\u00f3 Dr. Antoni Esteve","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/2021\/06\/29\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\/","og_locale":"ca_ES","og_type":"article","og_title":"La troballa d'una prote\u00efna implicada en el principal c\u00e0ncer de fetge, Premi de Recerca Fundaci\u00f3 Dr. Antoni Esteve - Fundaci\u00f3 Dr. Antoni Esteve","og_description":"El 2019, un grup del Centro Nacional de Investigaciones Cardiovasculares publicava a la revista Nature dades rellevants al voltant de la implicaci\u00f3 de la prote\u00efna p38gamma en el desenvolupament del principal tipus de c\u00e0ncer primari de fetge. Es tracta del carcinoma hepatocel\u00b7lular, que afecta m\u00e9s d’un mili\u00f3 de persones a l’any a tot el m\u00f3n","og_url":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/2021\/06\/29\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\/","og_site_name":"Fundaci\u00f3 Dr. Antoni Esteve","article_published_time":"2021-06-29T08:24:52+00:00","article_modified_time":"2024-03-24T14:51:07+00:00","og_image":[{"width":1365,"height":768,"url":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/wp-content\/uploads\/sites\/3\/2021\/06\/iStock-1212392754.jpg","type":"image\/jpeg"}],"author":"Pol Morales","twitter_card":"summary_large_image","twitter_misc":{"Escrit per":"Pol Morales","Temps estimat de lectura":"4 minuts"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/2021\/06\/29\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\/#article","isPartOf":{"@id":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/2021\/06\/29\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\/"},"author":{"name":"Pol Morales","@id":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/#\/schema\/person\/a1687300e23b0ac2ab84495a03182823"},"headline":"La troballa d’una prote\u00efna implicada en el principal c\u00e0ncer de fetge, Premi de Recerca Fundaci\u00f3 Dr. Antoni Esteve","datePublished":"2021-06-29T08:24:52+00:00","dateModified":"2024-03-24T14:51:07+00:00","mainEntityOfPage":{"@id":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/2021\/06\/29\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\/"},"wordCount":911,"commentCount":0,"image":{"@id":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/2021\/06\/29\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\/#primaryimage"},"thumbnailUrl":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/wp-content\/uploads\/sites\/3\/2021\/06\/iStock-1212392754.jpg","keywords":["c\u00e0ncer de fetge"],"articleSection":["Uncategorized"],"inLanguage":"ca","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/2021\/06\/29\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/2021\/06\/29\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\/","url":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/2021\/06\/29\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\/","name":"La troballa d'una prote\u00efna implicada en el principal c\u00e0ncer de fetge, Premi de Recerca Fundaci\u00f3 Dr. Antoni Esteve - Fundaci\u00f3 Dr. Antoni Esteve","isPartOf":{"@id":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/#website"},"primaryImageOfPage":{"@id":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/2021\/06\/29\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\/#primaryimage"},"image":{"@id":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/2021\/06\/29\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\/#primaryimage"},"thumbnailUrl":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/wp-content\/uploads\/sites\/3\/2021\/06\/iStock-1212392754.jpg","datePublished":"2021-06-29T08:24:52+00:00","dateModified":"2024-03-24T14:51:07+00:00","author":{"@id":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/#\/schema\/person\/a1687300e23b0ac2ab84495a03182823"},"breadcrumb":{"@id":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/2021\/06\/29\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\/#breadcrumb"},"inLanguage":"ca","potentialAction":[{"@type":"ReadAction","target":["https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/2021\/06\/29\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\/"]}]},{"@type":"ImageObject","inLanguage":"ca","@id":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/2021\/06\/29\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\/#primaryimage","url":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/wp-content\/uploads\/sites\/3\/2021\/06\/iStock-1212392754.jpg","contentUrl":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/wp-content\/uploads\/sites\/3\/2021\/06\/iStock-1212392754.jpg","width":1365,"height":768,"caption":"\/iStock"},{"@type":"BreadcrumbList","@id":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/2021\/06\/29\/la-troballa-duna-proteina-implicada-en-el-principal-cancer-de-fetge-premi-de-recerca-fundacio-dr-antoni-esteve\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Portada","item":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/"},{"@type":"ListItem","position":2,"name":"La troballa d’una prote\u00efna implicada en el principal c\u00e0ncer de fetge, Premi de Recerca Fundaci\u00f3 Dr. Antoni Esteve"}]},{"@type":"WebSite","@id":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/#website","url":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/","name":"Fundaci\u00f3 Dr. Antoni Esteve","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"ca"},{"@type":"Person","@id":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/#\/schema\/person\/a1687300e23b0ac2ab84495a03182823","name":"Pol Morales","image":{"@type":"ImageObject","inLanguage":"ca","@id":"https:\/\/secure.gravatar.com\/avatar\/6c5799ee792676e22d7558d1f109ddf8098905c75b14bcf15d23ecb7f422b189?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/6c5799ee792676e22d7558d1f109ddf8098905c75b14bcf15d23ecb7f422b189?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/6c5799ee792676e22d7558d1f109ddf8098905c75b14bcf15d23ecb7f422b189?s=96&d=mm&r=g","caption":"Pol Morales"},"url":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/author\/pmorales\/"}]}},"_links":{"self":[{"href":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/wp-json\/wp\/v2\/posts\/114","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/wp-json\/wp\/v2\/users\/356"}],"replies":[{"embeddable":true,"href":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/wp-json\/wp\/v2\/comments?post=114"}],"version-history":[{"count":1,"href":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/wp-json\/wp\/v2\/posts\/114\/revisions"}],"predecessor-version":[{"id":238,"href":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/wp-json\/wp\/v2\/posts\/114\/revisions\/238"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/wp-json\/wp\/v2\/media\/116"}],"wp:attachment":[{"href":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/wp-json\/wp\/v2\/media?parent=114"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/wp-json\/wp\/v2\/categories?post=114"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/wp-json\/wp\/v2\/tags?post=114"},{"taxonomy":"tipo","embeddable":true,"href":"https:\/\/diarisanitat.cat\/fundacio-dr-antoni-esteve\/wp-json\/wp\/v2\/tipo?post=114"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}