{"id":464,"date":"2022-12-05T14:00:19","date_gmt":"2022-12-05T14:00:19","guid":{"rendered":"https:\/\/diarisanitat.cat\/recerca-en-salut\/?p=464"},"modified":"2024-07-08T15:14:43","modified_gmt":"2024-07-08T15:14:43","slug":"un-nou-estudi-vol-detectar-el-parkinson-en-fase-primerenca-per-revertir-lo","status":"publish","type":"post","link":"https:\/\/diarisanitat.cat\/recerca-en-salut\/blog\/2022\/12\/05\/un-nou-estudi-vol-detectar-el-parkinson-en-fase-primerenca-per-revertir-lo\/","title":{"rendered":"Un nou estudi vol detectar el Parkinson en fase primerenca per revertir-lo"},"content":{"rendered":"

L\u2019estudi se centra en fer un q\u00fcestionari on line (https:\/\/www.cervellsaludable.cat\/es\/<\/strong><\/a>) a unes 10.000 persones entre 50 i 80 anys a Catalunya. D\u2019aquestes, es preguntar\u00e0 a 2.600 si poden despla\u00e7ar-se a casa seva a fer un test d\u2019olfacte i, en una fase m\u00e9s avan\u00e7ada, faran seguiment presencial a la cl\u00ednica a entre 200 i 300 persones, tant d\u2019alt risc com de baix risc.<\/p>\n

El projecte rep el nom d\u2019\u2018Envelliment cerebral saludable\u2019 (HeBA, de l\u2019angl\u00e8s \u2018Healthy Brain Aging\u2019) i, a m\u00e9s de la Unitat de Parkinson de l\u2019Hospital Cl\u00ednic de Barcelona, hi col\u00b7laboren centres d\u2019investigaci\u00f3 d\u2019Alemanya i \u00c0ustria, que tamb\u00e9 s\u2019encarreguen de fer q\u00fcestionaris als seus pa\u00efsos. El promotor d\u2019aquesta iniciativa \u00e9s la\u00a0Fundaci\u00f3 Michael J.Fox<\/a>\u00a0per a la investigaci\u00f3 del Parkinson.<\/p>\n

La investigadora principal del projecte al Cl\u00ednic, la doctora Maria Josep Mart\u00ed, explica que es nodreixen d\u2019investigacions anteriors segons les quals les persones amb Parkinson pr\u00e8viament han patit durant anys diferents problemes de salut, com p\u00e8rdua d\u2019olfacte, malsons, falta de mem\u00f2ria o depressi\u00f3.<\/p>\n

\u201cAquests s\u00edmptomes apareixen molt abans que la tremolor i l\u2019alentiment motor. El 80% dels pacients afirmen que han perdut olfacte, amb diferents graduacions, segons el cas. Entre el 30% i el 40% han tingut malsons a la nit, cridant i movent-se, fins i tot hi ha gent que ha caigut del llit. Sovint, han patit ansietat o estrenyiment. A m\u00e9s, ser home \u00e9s un factor m\u00e9s de risc, i no haver fumat mai tamb\u00e9 \u00e9s un factor de risc\u201d, resumeix la neur\u00f2loga.<\/p>\n

Un cop contestades preguntes diverses sobre aquests i altres s\u00edmptomes, s\u2019aplica una f\u00f3rmula, i el programa inform\u00e0tic estableix si la persona t\u00e9 un risc alt o baix de desenvolupar la malaltia.<\/p>\n

Objectiu: detenir la malaltia<\/h3>\n

El Parkinson \u00e9s un trastorn neurodegeneratiu que progressa lentament i afecta el sistema nervi\u00f3s central. Apareix quan entre el 50 i el 70% de les c\u00e8l\u00b7lules que produeixen la dopamina han redu\u00eft la capacitat de produir aquest neurotransmissor. Normalment, la mort de les neurones comen\u00e7a molts anys abans dels cl\u00e0ssics s\u00edmptomes, i \u00e9s aqu\u00ed on se centra la investigaci\u00f3.<\/p>\n

\"\"<\/a>
Mart\u00ed: \u201cQuan apareixen els s\u00edmptomes t\u00edpics i els pacients van lents a l\u2019hora de caminar, ja \u00e9s molt tard\u201d | Cedida<\/figcaption><\/figure>\n

Mart\u00ed assenyala que l\u2019objectiu \u00e9s \u201cintentar veure si som capa\u00e7os, amb un q\u00fcestionari, de saber quines persones estan m\u00e9s en risc de patir la malaltia del Parkinson. Ens interessa perqu\u00e8 el que estem veient \u00e9s que quan apareixen els s\u00edmptomes t\u00edpics i els pacients van lents a l\u2019hora de caminar, ja \u00e9s molt tard\u201d.<\/p>\n

\u201cAvui dia hi ha bastants laboratoris que estan intentant fer medicaments per revertir la causa o parar la malaltia, per\u00f2 ha sigut un desengany, perqu\u00e8 arribem tard i no ha sigut exit\u00f3s. Per aix\u00f2, intentem buscar els pacients a edats m\u00e9s joves, per trobar un medicament efica\u00e7\u201d, afegeix.<\/p>\n

Tot i que se sap poc sobre aquesta fase primerenca, l\u2019equip m\u00e8dic considera que poder detectar les persones durant aquest per\u00edode, ajudaria a alentir, detenir o revertir el proc\u00e9s de la malaltia.<\/p>\n

Qui pot participar<\/h3>\n

La decisi\u00f3 de preguntar a persones a partir de 50 anys t\u00e9 a veure amb el fet que ja hi ha una traject\u00f2ria llarga de vida per recollir tots els s\u00edmptomes susceptibles d\u2019avisar del risc de tenir Parkinson, a part del valor gen\u00e8tic. Tot i aix\u00f2, en funci\u00f3 dels resultats, l\u2019experta no descarta que es pugui fer l\u2019estudi a persones de menys de 50 anys.<\/p>\n

El q\u00fcestionari poden fer-lo persones neurol\u00f2gicament sanes i tamb\u00e9 persones que tenen familiars amb malalties neurodegeneratives de la vellesa. En canvi, no poden participar en aquest projecte malalts de Parkinson, Alzheimer i altres trastorns neurol\u00f2gics del moviment, dem\u00e8ncia, vessament cerebral o esclerosi lateral amiotr\u00f2fica (ELA), ni persones que prenguin medicaci\u00f3 que pugui augmentar o desencadenar els s\u00edmptomes d\u2019una malaltia neurodegenerativa.<\/p>\n

A Espanya, el Parkinson afecta prop de 140.000 persones i, amb l\u2019envelliment de la poblaci\u00f3, es preveu que la xifra augmenti significativament en els pr\u00f2xims anys. Avui dia no hi ha un tractament curatiu per a les malalties neurodegeneratives.<\/p>\n","protected":false},"excerpt":{"rendered":"

El Parkinson \u00e9s la segona malaltia neurodegenerativa a nivell mundial, despr\u00e9s de l\u2019Alzheimer, i un dels seus inconvenients \u00e9s que es detecta de forma tardana quan apareixen les tremolors i problemes de mobilitat, per\u00f2 la malaltia es troba al cos anys abans que es faci visible. Per aix\u00f2, un nou estudi en qu\u00e8 participa l\u2019Hospital Cl\u00ednic intenta identificar les persones que tenen un alt risc de patir Parkinson anticipant-se als s\u00edmptomes motor de la malaltia amb l\u2019objectiu d\u2019aturar-la o fins i tot revertir-la.<\/p>\n","protected":false},"author":725,"featured_media":465,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[126],"tags":[],"tipo":[],"class_list":{"0":"post-464","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-recerca"},"acf":[],"yoast_head":"\nUn nou estudi vol detectar el Parkinson en fase primerenca per revertir-lo - Recerca en salut<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/diarisanitat.cat\/recerca-en-salut\/blog\/2022\/12\/05\/un-nou-estudi-vol-detectar-el-parkinson-en-fase-primerenca-per-revertir-lo\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Un nou estudi vol detectar el Parkinson en fase primerenca per revertir-lo - Recerca en salut\" \/>\n<meta property=\"og:description\" content=\"El Parkinson \u00e9s la segona malaltia neurodegenerativa a nivell mundial, despr\u00e9s de l\u2019Alzheimer, i un dels seus inconvenients \u00e9s que es detecta de forma tardana quan apareixen les tremolors i problemes de mobilitat, per\u00f2 la malaltia es troba al cos anys abans que es faci visible. 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